Proton-Detected Solid-State NMR Spectroscopy of Bone with Ultrafast Magic Angle Spinning

Ultrafast high-resolution magic-angle-spinning NMR spectroscopy.

We demonstrate the acquisition of ultrafast 2D NMR spectra of semi-solid samples, with a high-resolution magic-angle-spinning setup. Using a recent double-quantum NMR pulse sequence in optimised synchronisation conditions, high-quality 2D spectra can be recorded for a sample under magic-angle spinning. An illustration is given with a semi-solid sample of banana pulp.

Double-resonance magic angle coil spinning.

We present an extension of magic angle coil spinning (MACS) solid-state NMR spectroscopy to double-resonance experiments, enabling implementation of powerful double-resonance solid-state NMR methodologies including cross polarization, proton decoupling, and two-dimensional correlation spectroscopy etc., while still enjoying the merits that are intrinsic to MACS, such as high concentration sensi...

Proton chemical shift anisotropy measurements of hydrogen-bonded functional groups by fast magic-angle spinning solid-state NMR spectroscopy.

The suitability of fast MAS solid-state NMR spectroscopy for probing (1)H chemical shift anisotropy of hydrogen-bonded species has been demonstrated.

Supporting Information: Proton-Selective 17O–1H Distance Measurements in Fast Magic-Angle-Spinning Solid-State NMR Spectroscopy for the Determination of Hydrogen Bond Lengths

A Novel High-Resolution and Sensitivity-Enhanced Three-Dimensional Solid-State NMR Experiment Under Ultrafast Magic Angle Spinning Conditions

Although magic angle spinning (MAS) solid-state NMR is a powerful technique to obtain atomic-resolution insights into the structure and dynamics of a variety of chemical and biological solids, poor sensitivity has severely limited its applications. In this study, we demonstrate an approach that suitably combines proton-detection, ultrafast-MAS and multiple frequency dimensions to overcome this ...